I have the same problem... When I start up AC Odyssey with the sensor panel displaying on a 2nd monitor, the sensor panel shifts to the right on my 2nd monitor, thus hiding over half of the sensor panel offscreen. When I close the game, it returns to normal. Also, of I press the windows key to return to my desktop with the game still running, it also shifts back into place and stays that way, even if I go back into the game. Furthermore, while playing the game, I get constant fps drops and screen stutters. When I shut down Aida64 that stops, and I get a consistent buttery-smooth 60 fps.
You asked if Mip was running an Asus motherboard. Is this of any importance?
I'm running a z390 Asus ROG Maximus XI Hero.
Thanks in advance for your reply.