I too have been using Samsung SPF (87H) in Windows 10 for years; without any realy problems I might add.
I don't have it running every day, so I don't know when it stopped working, but it's a bit odd...
When I start the display, it says "PC connected via USB cable".
I then select "Mini Monitor"; this always takes a few seconds; but while I can see in the Device Manager, that your "libusb-win32" driver is being loaded, it suddenly gets unloaded with a message displayed on the SPF: "Your photo frame must be connected tot he PC"
I've already tried a different USB cable and several USB ports (back or front); as it was working at least a few weeks ago: could a Win-Upd have "broken" the driver?
I don't even have the latest version; only an up2date 1909...
Does this driver work for you? What's your Win10 version? Latest updates installed?
Thanks for any infos!